Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Atoh1  atonal bHLH transcription factor 1   (Synonyms: bHLHa14, Hath1, Math1)
Results	Reference
1	J:60393 Ben-Arie N, Hassan BA, Bermingham NA, Malicki DM, Armstrong D, Matzuk M, Bellen HJ, Zoghbi HY, Functional conservation of atonal and Math1 in the CNS and PNS. Development. 2000 Mar;127(5):1039-48
1*	J:180770 Bjerknes M, Khandanpour C, Moroy T, Fujiyama T, Hoshino M, Klisch TJ, Ding Q, Gan L, Wang J, Martin MG, Cheng H, Origin of the brush cell lineage in the mouse intestinal epithelium. Dev Biol. 2012 Feb 15;362(2):194-218
1	J:199162 Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK, Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12;33(24):10110-22
1*	J:195176 Driver EC, Sillers L, Coate TM, Rose MF, Kelley MW, The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea. Dev Biol. 2013 Apr 1;376(1):86-98
1	J:125313 Flora A, Garcia JJ, Thaller C, Zoghbi HY, The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15382-7
1	J:119485 Friedel RH, Kerjan G, Rayburn H, Schuller U, Sotelo C, Tessier-Lavigne M, Chedotal A, Plexin-B2 controls the development of cerebellar granule cells. J Neurosci. 2007 Apr 4;27(14):3921-32
1	J:188329 Huang WH, Tupal S, Huang TW, Ward CS, Neul JL, Klisch TJ, Gray PA, Zoghbi HY, Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809
1*	J:326361 Li S, Fan T, Li C, Wang Y, Li J, Liu Z, Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain. Dev Dyn. 2022 Jul;251(7):1156-1174
1	J:333396 Luo Z, Du Y, Li S, Zhang H, Shu M, Zhang D, He S, Wang G, Lu F, Liu Z, Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119850119
1	J:149981 Maricich SM, Wellnitz SA, Nelson AM, Lesniak DR, Gerling GJ, Lumpkin EA, Zoghbi HY, Merkel cells are essential for light-touch responses. Science. 2009 Jun 19;324(5934):1580-2
1	J:102293 Matei V, Pauley S, Kaing S, Rowitch D, Beisel KW, Morris K, Feng F, Jones K, Lee J, Fritzsch B, Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn. 2005 Nov;234(3):633-50
1*	J:154915 Morrison KM, Miesegaes GR, Lumpkin EA, Maricich SM, Mammalian Merkel cells are descended from the epidermal lineage. Dev Biol. 2009 Dec 1;336(1):76-83
1	J:298271 Nguyen MB, Valdes VJ, Cohen I, Pothula V, Zhao D, Zheng D, Ezhkova E, Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signalling. Exp Dermatol. 2019 Apr;28(4):374-382
1*	J:313342 Nichols DH, Bouma JE, Kopecky BJ, Jahan I, Beisel KW, He DZZ, Liu H, Fritzsch B, Interaction with ectopic cochlear crista sensory epithelium disrupts basal cochlear sensory epithelium development in Lmx1a mutant mice. Cell Tissue Res. 2020 Jun;380(3):435-448
1	J:217588 Perdigoto CN, Bardot ES, Valdes VJ, Santoriello FJ, Ezhkova E, Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network. Development. 2014 Dec;141(24):4690-6
1	J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7
1*	J:80025 Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ, The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan;130(1):221-32
1*	J:105185 Wang VY, Rose MF, Zoghbi HY, Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron. 2005 Oct 6;48(1):31-43
1	J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695
1	J:95110 Woods C, Montcouquiol M, Kelley MW, Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci. 2004 Dec;7(12):1310-8
1	J:337924 Wu SR, Butts JC, Caudill MS, Revelli JP, Dhindsa RS, Durham MA, Zoghbi HY, Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation. Sci Adv. 2023 Jun 30;9(26):eadg1671
1	J:234179 Xiao Y, Thoresen DT, Miao L, Williams JS, Wang C, Atit RP, Wong SY, Brownell I, A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet. 2016 Jul;12(7):e1006150
1*	J:248783 Xie WR, Jen HI, Seymour ML, Yeh SY, Pereira FA, Groves AK, Klisch TJ, Zoghbi HY, An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment. J Neurosci. 2017 Sep 6;37(36):8583-8594